Sunday, April 13, 2025

ECG Blog #477 — Is One or Both 3rd-Degree?


Compare these 2 tracings.
  • Is one or both of them 3rd-Degree (Complete) AV Block?
  • If not — Why not?

Figure-1: Is one or both of these tracings 3rd-Degree?

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Let's look at these rhythms one at a time — starting with Rhythm-B:

Rhythm B (which I have reproduced in Figure-2):
As always — I favor the Ps, Qs, 3R Approach for assessing rhythm disorders, as I find this the most time-efficient way to narrow down my differential diagnosis of arrhythmias (See ECG Blog #185):
  • NOTE #1: Lead MCL-1 is a right-sided monitoring lead (providing a comparable view to what we typically see in right-sided lead V1 on a 12-lead ECG).
  • NOTE #2: It does not matter in what order you assess the Ps,Qs,3Rs. I often vary the sequence I use depending on which parameter is easiest to assess in the tracing I am looking at.
  • NOTE #3: If you have a moment of time (ie, If the patient in front of you is not about to have a cardiac arrest) — then using calipers will save you time (and increase your accuracy) for interpreting challenging rhythms.

Figure-2: This is Tracing-B from today's case.

Applying the Ps, Qs, 3Rs to Rhythm-B:
  • P waves are present. We see lots more P waves than QRS complexes (I've labeled with RED arrows in Figure-3 those P waves that we clearly see).
  • The QRS complex is wide ( = 0.15 second). I find it easiest to measure QRS duration by selecting a complex that either begins or ends on a heavy ECG grid line (In Figure-3 — Beat #1 ends on a heavy grid line).

And — The 3Rs (ie, Is the rhythm Regular? — the Rate? — and are P waves Related to neighboring QRS complexes?):
  • The R-R interval in Figure-2 is Regular — and measures just under 8 large boxes in duration (and 300 ÷ a bit less than 8 = a Rate slightly less than 40/minute).
Are P waves Related to neighboring QRS complexes
  • Look at the PR interval in front of each QRS in Figure-3. Doesn't the PR interval continually change?

Figure-3: The QRS in Tracing-B is clearly wide. I've labeled those P waves that we clearly see with RED arrows.

QUESTION:
Is the atrial rhythm in Figure-3 regular?
  • Given the regularity of the RED arrows that we do see in Figure-3 — Wouldn't it make more sense for the rest of the underlying atrial rhythm to be regular, instead of all-of-a-sudden dropping several P waves?

  • PEARL #1: Use calipers to answer the above Question! (See the PINK arrows in Figure-4).

Figure-4: I've added PINK arrows to show where my calipers suggest that on-time P waves are likely to be hiding.

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ANSWER:
Although impossible to prove from the short single-lead tracing we show in Figure-4 — it makes much more sense for the underlying atrial rhythm to be regular (instead of having to postulate sudden and unpredictable onset of some unusual type of intermittent SA block).
  • Setting your calipers to the P-P interval between any 2 consecutive RED arrows in Figure-4 — allows us to predict the probable location of underlying on-time sinus P waves ( = PINK arrows in Figure-4).
  • PEARL #2: As shown in ECG Blog #344 — it is common in patients with 2nd-degree or 3rd-degree AV block to manifest slight variation in the P-P interval of underlying sinus P waves. This slight variation in the rate of sinus P waves is known as "ventriculophasicsinus arrhythmia — and is easy to account for when postulating the probable location of hidden "on-time" sinus P waves.

Putting It All Together for Tracing-B:
The rhythm in Tracing-B is 3rd-Degree (Complete) AV Block.
  • PEARL #3: Complete (or 3rd-degree) AV block — is said to be present when none of the on-time sinus impulses from above are able to conduct to the ventricles despite having an adequate opportunity to do so.

  • KEY Point: It is this last requirement (ie, the need for "adequate opportunity" to conduct) — that is so commonly overlooked. There may be AV dissociation, with none of the on-time P waves in the small segment of the rhythm you are looking at being able to conduct — but unless the ventricular rate is slow enough (usually less than 55-60/minute)  and, unless the duration of monitoring is long enough — it may be that there has not yet been enough of a monitoring period to demonstrate that the degree of AV block is complete.

I illustrate the above concept in more detail in ECG Blog #191 (in which I also review the 3 types of AV Dissociation, of which AV block is only one of these types). For now, the "Take-Home" Point is that Tracing-B in today's case does show 3rd-Degree (Complete) AV Block. Note the following features of this rhythm in Figure-5:
  • The ventricular rhythm is slow, regular — and with a wide QRS complex.
  • The atrial rhythm is regular (RED arrows — showing no more than slight variation in the R-R interval, consistent with ventriculophasic sinus arrhythmia).
  • There is complete AV dissociation — because none of the on-time sinus P waves are related to neighboring QRS complexes (ie, The PR interval in front of each QRS complex continually changes).
  • More than just AV dissociation, there is complete AV Block  because on-time sinus P waves occur at all points within the R-R interval, and fail to conduct despite having more than adequate opportunity to do so.
  • The level of this AV block is below the AV Node (and therefore arising from the ventricles) — because there is a slow idioventricular escape rate (ie, with QRS widening — and an "escape" rate of just under 40/minute).

Figure-5: Tracing-B shows complete AV block.


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What about Tracing-A in today's case? (reproduced in Figure-6):

Figure-6: This is Tracing-A from today's case. (To improve visualization — I've digitized the original ECG using PMcardio).

My First Impression of Tracing-A:
The 12-lead ECG in Tracing-A is obviously abnormal. The marked T wave inversion in leads V1,V2 is impossible to overlook! 
  • The rhythm is extremely slow. 
  • Looking at just the last 2 beats (that occur in simultaneously-recorded leads V1,V2,V3 — and in V4,V5,V6) — I could not initially tell which beats might be supraventricular (ie, with RBBB conduction in lead V1?) — vs ventricular (producing the wide QS complexes in V4,V5,V6?).
  • NOTE #4: In order to complete my interpretation — I would clearly need to determine which of the 4 beats in this tracing are ventricular vs supraventricular (and whether any of these 4 beats might be conducted?).
  • NOTE #5: As I turned my attention to the rhythm — it was also clear that using calipers would be needed. 

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Applying the Ps, Qs, 3Rs to Rhythm-A:
  • The QRS complex looks to be wide (about 3 little boxes = 0.12 second in duration).
  • As noted — the Rate is very slow (barely over 30/minute such that we only see 4 beats). The R-R interval looks to be the same between the first 3 beats — but beat #4 looks like it occurs early (It also appears that QRS morphology of beat #4 is different from that of the first 3 beats).
  • P waves are present. That said — it is hard to tell from simple inspection of the rhythm if the atrial rate is (or is not) regular.
  • As to whether P waves are Related to neighboring QRS complexes? — We need to look in front of each of the 4 QRS complexes. It certainly appears that the PR interval in front of each of the 4 beats in the long lead II rhythm strip is different.

My
Initial Impression of Rhythm-A:
I was not certain about the etiology of this rhythm.
  • Confession: Even after having had LOTS of time to contemplate Rhythm-AI am still not sure what is going on. Obviously — some form of severe heart block is present. Pacing is likely to be needed unless something "fixable" is quickly found. That said — I admittedly had more questions than answers about this rhythm.

Looking closer ...
  • Does beat #4 occur early? To answer this question — I carefully measured each R-R interval in the long lead II rhythm strip (See Figure-7).

Figure-7: Caliper measurements of each R-R interval.


ANSWER: Beat #4 clearly does occur early.
  • PEARL #4: Most of the time when there is significant AV block — the BEST clue that a beat may be conducted is if a beat occurs earlier-than-expected. As a result — I wondered if beat #4 might be conducted by the P wave that appears in front of this beat?

  • NOTE #6: It's important to realize that we have no idea of how long the pause was before beat #1nor do we have any idea of when beat #5 occurred (or if beat #5 occurred at all?)


Next QUESTION:
  • Are P waves regular in Rhythm-A?

In Figure-8 — I show my attempt to answer this question ...

Figure-8: I've labeled those P waves that we clearly see in Rhythm-A with RED arrows.

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ANSWER: As for PEARL #1 that we applied when problem-solving Rhythm-B — Using calipers facilitates (and expedites) predicting where additional P waves might be hiding.
  • PINK arrows in Figure-9 suggest logical "hiding spots" for the 3 missing P waves in Rhythm-A. Therefore, it is likely that the atrial rhythm is regular — and that 2 of the on-time sinus P waves are hidden within the QRS complexes of beats #1 and 3, with a 3rd P wave accounting for slight increase in the volume of the T wave of beat #2.

Figure-9: I've added PINK arrows to show where my calipers suggest that on-time P waves are likely to be hiding.


Putting IAll Together for Tracing-A:
I admit to not being certain of the etiology of Rhythm-A.
  • PEARL #5: As disappointing as my admission of not being certain about the interpretation of Rhythm-A might be — there is an important lesson in this admission: The etiology for every rhythm will not always be evident from a single short period of monitoring (ie, We only see 4 beats in Rhythm-A — so it is understandable that we might not yet appreciate what is going on)
  • Awareness that more information (ie, a longer period of monitoring) is needed — is an important concept to become comfortable with. 

What We DO Know about Rhythm-A:
The above said — We do know a lot about Rhythm-A:
  • At the least — there appears to be high-grade 2nd-Degree AV Block in Rhythm-A, with a very slow "escape" rate (just over 30/minute).
  • Beat #4 occurs early and manifests a different QRS morphology compared to the first 3 beats. As per PEARL #4 — the earlier-than-expected occurrence of beat #4 usually suggests that this beat may be conducted. That said — 2 findings are present in Rhythm-A that are against beat #4 being conducted. These findings are: i) That the PR interval preceding beat #4 in the long lead II rhythm strip looks surprisingly shorter than I would expect being able to conduct given how severe the AV block otherwise seems; and, ii) QRS morphology in simultaneously-recorded leads V4,V5,V6 for beat #4 looks much more like ventricular than conducted beats (ie, the wide QS complexes).
  • BUT — None of the P waves before beat #4 appear to have any relation to neighboring QRS complexes.

BOTTOM Line for Tracing-A:
 Whether beat #4 is conducted — or whether instead there is complete AV block with slightly early "escape" from another ventricular focus in the form of beat #4 is not apparent from this single tracing. What is known:
  • There is at-the-least high-grade 2nd-degree AV block with a very slow "escape" rate. As a result — pacing will be needed unless some "fixable" etiology for this slow rate can be found.
  • Although wide — QRS morphology for the first 3 beats looks like it is arising from somewhere within the conduction system (perhaps from the His — with RBBB conduction based on the QR pattern with predominant positivity in lead V1).
  • The deep Q in lead V1 — and the very deep T wave inversion in anterior leads suggests anterior infarction at some time in the recent past may be the reason for the severe AV block.
  • More information (and a longer period of monitoring) is needed to say more.


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Acknowledgment: My appreciation to Adem Ahmed (from Nouakchott, Mauritania) for the case and this tracing.

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Additional Relevant ECG Blog Posts to Today’s Case:

  • ECG Blog #185 — Use of a Systematic Approach to Rhythm Interpretation.
  • ECG Blog #191 — Is AV Block Complete? (Assessing AV Dissociation).


Other Posts on Assessing for AV Block:

— NOTE: There are even more cases relevant to assessment for AV Block on this Blog, but those below provide some “practice” for those in search of some example cases.



ADDENDUM:
  • What follows below is a 7-page excerpt from my ACLS-2013 Arrhythmias (Expanded Version) book, in which I review the distinction between AV dissociation vs complete AV block.


Today’s ECG Media PEARL #19a (6:45 minutes Audio) — Why is this Not Complete AV Block? This recording suggests a few Quick-Things-To-Do that help to rule in or rule out Complete AV Block (P.S.  I updated this Audio Pearl on 10/12/2021).






ECG Media Pearl #8 (8:20 minutes Video) — ECG Blog #191 — Distinguishing between ADissociation vs Complete AV Block (2/6/2021).




ECG Media Pearl #9 (5:40 minutes Video) — ECG Blog #192 — Reviews the 3 Causes of AV Dissociation (2/9/2021).





















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